In today’s CBD health news, learn more about many treatment-resistant kinds of pediatric epilepsy that can be mitigated by CBD, according to a new study. Meanwhile, along with colleagues, Dr. Justin Cole is conducting a study on the impact of cannabidiol (CBD) products on children with mental health issues. Lastly, the North Carolina Senate approved a bill authorizing the medical use of cannabis.
CBD Reduces Seizures in Treatment-resistant Pediatric Epilepsy
Original Source: Researchers show how CBD can reduce seizures in treatment-resistant forms of childhood epilepsy
Cannabidiol (CBD), a non-psychoactive component of cannabis, can lessen seizures in many treatment-resistant forms of pediatric epilepsy, according to Aston University researchers.
CBD suppressed signals carried by a chemical called lysophosphatidylinositol, according to NYU Grossman School of Medicine experts and Aston University researchers (LPI).
LPI is located in brain neurons and amplifies nerve signals, however some epilepsies hijack it to cause seizures.
CBD reduces LPI’s ability to enhance neuronal signals in the hippocampus, according to the Neuron study.
For the first time, the molecule inhibits signals that counter seizures, explaining the value of CBD treatment and the production of seizure activity in epileptics.
The Aston University study team recorded electrical impulses in brain cells from epileptic animals, some of which had been treated with CBD, using Professor Gavin Woodhall’s leading epilepsy model. By doing this, they were able to identify CBD’s chemical pathways of seizure prevention in epileptic brains.
Professor Woodhall, co-director of Aston Centre for Health and Neurodevelopment, said: “These new insights into epilepsy and the mechanism by which CBD works to reduce seizures is the fruit of years of collaboration between neuroscientists in the UK and USA and our industrial partner, GW Pharma.”
“We believe it will lead to better treatments.”
“We are thrilled that our epilepsy model is being utilized to achieve such substantial advancements in epilepsy processes and is paving the path for a larger spectrum of future treatments.”
Aston Centre for Health and Neurodevelopment senior neuroscience lecturer Dr. Stuart Greenhill
Richard W. Tsien, chair of NYU Langone Health’s Department of Physiology and Neuroscience, said, “Our results extend the field’s understanding of a central seizure-inducing mechanism, with many implications for the search of innovative treatment options.”
The study also explained how brain circuits are balanced and how CBD prevents seizures. Autism and schizophrenia have related abnormalities, thus the paper may have a wider impact.”
The findings focus on how each neuron “fires” to send an electrical pulse down an extension of itself until it reaches a synapse, the gap that joins it to the next cell in a neural pathway, and how this activity might shift in a network likely to cause epileptic seizures.
CBD Research Guides Children’s Health
Original Source: RESEARCH ON CBD: INFORMING CHILDREN’S HEALTH DECISIONS
Community health involves educating the public about safe and effective medical choices. Dr. Justin Cole, associate professor of pharmacy practice at Cedarville University’s School of Pharmacy, is conducting a study with colleagues on the impact of cannabidiol (CBD) products on children with mental health issues. Justin Cole’s headshot.
Cole, Dr. Aleda Chen, associate dean and professor of pharmacy practice, and Katie Schwaller and Zach Krauss, fourth-year Doctor of Pharmacy students from Washington Township, Ohio, and Temple, Texas, respectively, investigated the effects of unlicensed CBD products on children with anxiety, autism, or ADHD.
Cole noted that parents of children with severe diseases are increasingly using unregulated CBD products. No one has quantified this until now. We wanted to put a number to this and begin to grasp their conception of these goods to maybe assist future safe medical decisions.”
Cedarville’s pharmacy leaders and students revealed that over 30% of parents have given their children unapproved CBD products for anxiety or other neurodevelopmental disorders. They also discovered that parents who did so generally liked these goods and believed the community supported their usage on children.
Cole added, “Parents are looking for ways to help their children with more pervasive challenges.” “Despite warnings, they are turning to these unregulated CBD products.”
For kids with anxiety, autism, or ADHD, the FDA has not approved any CBD products. So, parents’ CBD purchases are uncontrolled, regardless of legality.
Cole stated, “These things are labeled falsely.” One research found 31% of these goods to be label-accurate. We don’t know what these kids are eating. No effectiveness data exists either. These products may not be safe or effective.”
Informing the public is important because safety is a growing problem.
“We want parents to understand that these goods could be a hazard to their child’s safety,” Cole added. There were no poison control calls concerning kids consuming CBD products in 2014. In 2021, these numbers exceeded 3,500. We want parents to know about potential dangers.”
Cole acknowledges his two Doctor of Pharmacy students for their commitment to community health.
Cole said, “The children were important in making this endeavor a success.” “Katie (Schwaller) led this research, guiding us to a full study. Zach (Krauss) helped create our parent survey and collected data for our findings. This wouldn’t have gone so well without them. They show God’s talent in various ways.”
The study was presented at the Pediatric Pharmacy Association meeting in September and the American College of Clinical Pharmacy conference in October. The Journal of Pediatric Pharmacology and Therapeutics will publish the entire study this summer.
Cedarville University, a Christ-centered, Baptist university in southwest Ohio, enrolls 5,082 undergraduate, graduate, and dual-enrolled high school students in more than 175 majors. Cedarville, one of Ohio’s largest private universities, was founded in 1887 and is known nationally for its authentic Christian community, rigorous academic programs, including the Doctor of Pharmacy program, high graduation and retention rates, accredited professional and health science offerings, and the #4 national ranking by the Wall Street Journal for student engagement.
NC Senate Approves Chronic Illness Marijuana Bill
Original Source: Bill to legalize marijuana for chronic illness care passes in NC Senate
The North Carolina Senate passed a medical marijuana bill at 4:20 p.m. on March 1.
The “N.C. Compassionate Care Act” legalizes medical marijuana for cancer, post-traumatic stress disorder, HIV/AIDS, and other chronic diseases.
The state House must pass the bill before Gov. Roy Cooper signs or vetoes it. S.B. 3 cleared the state Senate 36 to 10 with bipartisan support, but its fate is unknown in the House.
The “N.C. Compassionate Care Act” passed the Senate last year but died in the House.
This year’s bill allows qualifying patients or caregivers to acquire cannabis from licensed dispensaries with an ID card.
According to the measure, physicians who provide written certifications must take a 10-hour course and further training. To assess cannabis’s efficacy, they will have to review patients periodically.
According to the bill’s legislative fiscal note, it would raise state revenue. The majority of revenue is expected to come from patient and caregiver registry card application fees and gross receipt fees.
Sen. Graig Meyer (D-Caswell, Orange, Person) has prioritized legalizing, taxing, regulating, and decriminalizing marijuana. He hopes it passes this year and becomes recreational.
Meyer stated, “I’m extremely bullish about Raleigh’s talks and people’s interest in this across the state.” “And I do think that legislation will likely move forward this year.”
He also wants the law to fully decriminalize marijuana, explain where marijuana tax income will go, and eliminate a “vertical market.”
The vertical market allows corporations to manage product growth, production, distribution, and sales. Meyer predicted that big firms will run the industry.
Meyer stated, “We need to reverse the detrimental effects of marijuana criminalization.” “And we need to make sure that everyone who’s been convicted of a crime that they wouldn’t be eligible to be convicted of when this law goes into force gets their sentences erased.”
Meyer said that CBD retailers are not the bill’s priority. These stores sell marijuana products without tetrahydrocannabinol (THC). Delta-8, an intoxicating CBD product, needs regulation in North Carolina.
Nevertheless, Jane Allred, Asheville Hemp Farms’ business manager, claimed cannabis legalization could hurt her company.
“North Carolina wants everything government-regulated like our ABC stores,” ” “They want to do something similar with marijuana as far as the only facilities to enter and purchase items would be government owned and operated, which does undermine a lot of our free market.”
Marijuana assisted Allred with addiction, recovery, and persistent mental illness. They also worry about medical marijuana’s price since it will be regulated by the government.
Medical marijuana operations concerned UNC Eshelman School of Pharmacy clinical associate professor Amanda Corbett.
She hopes the state looks ahead to ensure prescribers, dispensers, patients, and caregivers have everything they need and can safely distribute cannabis.
But, she added that patients shouldn’t have to migrate to other states if cannabis is available.
Corbett wants North Carolina’s pharmacists and dispensaries to follow other states’ standards.
38 states allow medical cannabis.
According to Corbett, medical marijuana helps patients. She also noted cancer and HIV patients had taken medical marijuana for pain and found it helpful.
“It’s going to be predicated on looking at the data very carefully with the product that will be authorized to be produced, dispensed, provided straight to the patient and having very clear recommendations around in North Carolina,” she said.
Summary of Today’s CBD Health News
Overall, Cannabidiol (CBD), a nonpsychoactive component of cannabis, has been shown to lessen seizures in many forms of treatment-resistant pediatric epilepsy, and this finding was made possible by research conducted at Aston University.
On the other hand, Dr. Justin Cole, an associate professor in Cedarville University’s School of Pharmacy, is leading a study on the impact of cannabidiol (CBD) products on children with mental health difficulties. They hoped to learn how children with anxiety, autism, or ADHD reacted to CBD products that hadn’t been approved for sale in the United States.
Finally, a medicinal marijuana bill was recently approved by the North Carolina Senate. The “N.C. Compassionate Care Act,” or Senate Bill 3, legalizes the use of medical marijuana for people with terminal diseases like cancer, PTSD, HIV/AIDS, and other debilitating conditions.
